Antacids Explained: How Different Ingredients Help Control Acid Reflux
Acid reflux and heartburn affect millions of people worldwide, making antacid suspension one of the most sought-after remedies for quick relief. Among the leading manufacturers in this segment, Eskag Pharma Pvt. Ltd. has established itself as a trusted name in pharmaceutical formulations, including high-quality antacid oral suspensions. With a strong commitment to innovation, safety, and efficacy, Eskag Pharma produces advanced antacid suspension syrup formulations that offer fast-acting and long-lasting relief from acid reflux, heartburn, and indigestion. Backed by state-of-the-art manufacturing facilities and stringent GMP and WHO guidelines, the company ensures consistent quality and effectiveness in every batch. As a leading antacid suspension manufacturer, Eskag Pharma also provides third-party manufacturing and contract manufacturing services for pharmaceutical brands seeking high-quality formulations. Whether for over-the-counter (OTC) sales or prescription-based treatments, Eskag Pharma’s antacids for acid reflux are formulated to deliver optimal patient outcomes. In this blog, we explore the mechanism, benefits, and key ingredients of antacid suspensions, helping you understand how they work and why they are a preferred choice for managing acid reflux.
Acid reflux and heartburn are common digestive issues affecting millions worldwide. To manage these conditions, antacid suspension has emerged as one of the most effective solutions. Unlike tablets or chewable antacids, antacid suspension syrup provides fast relief by neutralizing stomach acid and soothing the esophagus.
In this blog, we will explore how different ingredients in antacid suspensions work, their benefits, and how to choose the best syrup for acid reflux.
What is an Antacid Suspension?
An antacid suspension is a liquid formulation designed to neutralize excess stomach acid, providing relief from heartburn and acid reflux. Unlike solid antacids, liquid suspensions work faster and coat the esophagus, reducing irritation.
Key features of an antacid oral suspension:
- Acts quickly to neutralize stomach acid
- Provides a protective layer over the stomach lining
- Ideal for individuals who have difficulty swallowing pills
- Often contains a combination of magaldrate, aluminum hydroxide, and magnesium hydroxide
Patients often seek the best antacids for heartburn, and liquid suspensions provide an ideal solution due to their quick action and long-lasting effects.
How Antacid Suspension Works for Acid Reflux Relief
When we consume food, stomach acid plays a crucial role in digestion. However, excessive acid production can lead to acid reflux, heartburn, and gastritis. This is where an antacid suspension comes into play.
Mechanism of Action
1. Neutralization of Stomach Acid
The primary function of an antacid suspension is to neutralize excess stomach acid, which alleviates discomfort and prevents acid from irritating the esophagus.
- Ingredients such as magaldrate, calcium carbonate, and magnesium hydroxide work by reacting with hydrochloric acid (HCl) in the stomach, reducing its acidity.
- Magaldrate is a unique component that gradually releases both aluminum hydroxide and magnesium hydroxide, ensuring a balanced and sustained neutralization effect.
- Calcium carbonate provides rapid but short-term relief, while magnesium hydroxide offers a longer-lasting effect without causing rebound acid secretion.
This process raises the stomach’s pH level, reducing acidity and making it less likely to cause heartburn or reflux.
2. Protective Coating Over the Stomach and Esophagus
Some antacid oral suspensions contain additional protective agents like sodium alginate that create a physical barrier against acid reflux.
- Sodium alginate reacts with gastric acid to form a viscous gel-like layer on top of the stomach contents.
- This floating barrier prevents acid from rising into the esophagus, reducing the likelihood of heartburn, regurgitation, and GERD symptoms.
- The coating effect also helps in reducing irritation caused by previously damaged esophageal tissue.
This mechanism is especially beneficial for patients with chronic acid reflux, as it prevents long-term damage to the esophagus lining.
3. Reduction of Gas Formation and Bloating
Many antacid suspensions also contain simethicone, an anti-foaming agent that helps reduce gas and bloating.
- When excess acid production leads to bloating and discomfort, simethicone helps break down gas bubbles in the stomach and intestines.
- This reduces bloating, belching, and feelings of fullness, which often accompany acid reflux.
- By relieving trapped gas, simethicone prevents additional pressure on the stomach, reducing the likelihood of acid reflux episodes.
Why Antacid Suspension is More Effective Than Solid Forms?
Antacids are available in various forms, including tablets, chewables, and liquid suspensions. However, antacid suspension syrup has been found to be more effective due to its faster action, superior coating effect, and multi-functional formulation. Let’s explore the reasons why liquid antacid oral suspension is preferred over solid forms.
Faster Absorption and Immediate Relief
One of the key advantages of antacid suspension syrup over chewable tablets and capsules is its rapid absorption and immediate effect.
- Liquid formulations do not require breakdown or digestion, unlike tablets that must first dissolve in the stomach.
- When consumed, the suspension starts working immediately, as the active ingredients are already in a dispersed form, allowing them to react with stomach acid instantly.
- In contrast, solid antacids take longer to dissolve in the stomach, delaying relief from acid reflux symptoms.
Because of this quick absorption, antacid suspensions are ideal for patients experiencing sudden, severe heartburn or acid reflux.
Better Coating Effect for Long-Lasting Protection
Another major benefit of antacid suspension over tablets or chewables is its ability to coat the stomach lining and esophagus, providing relief that lasts longer.
- Suspensions contain ingredients like sodium alginate, magnesium hydroxide, and aluminum hydroxide, which form a protective barrier over the stomach lining.
- This coating prevents direct contact of gastric acid with the esophagus, reducing irritation, burning sensations, and inflammation.
- In contrast, chewable tablets and capsules do not offer this coating effect, leaving the esophagus vulnerable to acid damage.
This feature makes liquid antacids particularly beneficial for chronic acid reflux sufferers and GERD (Gastroesophageal Reflux Disease) patients.
Multi-Action Formula for Comprehensive Relief
Many antacid suspensions contain a combination of acid-neutralizing agents, gas-reducing compounds, and protective ingredients, providing multi-functional relief that chewable tablets cannot match.
- Neutralization of Acid – Ingredients like magaldrate, calcium carbonate, and magnesium hydroxide work instantly to reduce stomach acidity, preventing heartburn.
- Protective Coating – Sodium alginate forms a barrier that shields the esophagus from rising acid, reducing irritation and long-term damage.
- Reduction of Gas and Bloating – Some antacid suspensions include simethicone, which breaks down gas bubbles and relieves bloating and discomfort.
This three-in-one action makes liquid antacid suspension syrup superior to chewable tablets, which generally only neutralize acid without additional protective or anti-gas benefits.
Convenience and Ease of Use
For many people, liquid antacids are easier to consume compared to solid forms.
- Some individuals, especially older adults and people with swallowing difficulties, struggle to take tablets or chewables.
- Liquid suspensions offer a smooth and easy-to-swallow alternative, ensuring better compliance and effectiveness.
- Additionally, liquid suspensions allow for flexible dosing, meaning the user can take the exact amount needed rather than being restricted to fixed tablet doses.
Why Liquid Antacid Suspension is the Preferred Choice for Acid Reflux Sufferers
| Feature | Antacid Suspension | Tablets/Chewables |
| Speed of Action | Immediate effect as no digestion is needed | Slower as the tablet must dissolve |
| Coating & Protection | Forms a protective layer over the esophagus | No coating effect |
| Multi-Action Formula | Neutralizes acid + coats the stomach + reduces gas | Primarily neutralizes acid |
| Ease of Consumption | Easy to swallow and dose | Some people may struggle to swallow tablets |
| Ideal for Chronic GERD Patients | ✅ Yes | ❌ No |
Because of these benefits, antacid suspension syrup remains the best syrup for acid reflux, offering rapid and comprehensive relief.
Considering all the advantages of faster relief, better coating, and multi-functional action, antacid suspensions are the preferred choice for individuals suffering from acid reflux, heartburn, and GERD.
Key Ingredients in Antacid Suspensions
Each antacid oral suspension contains carefully selected ingredients to enhance its effectiveness. Let’s examine the primary components:
Magaldrate – The Active Ingredient
Magaldrate is a complex of aluminum hydroxide and magnesium hydroxide, widely used in antacid suspension formulations.
Magaldrate Antacid Benefits:
- Rapidly neutralizes stomach acid
- Provides long-lasting relief compared to single-component antacids
- Helps reduce peptic ulcers and gastric discomfort
- Less risk of constipation (compared to aluminum-based antacids) or diarrhea (compared to magnesium-based antacids)
Because of its balanced properties, magaldrate-based antacid suspension is often considered the best syrup for acid reflux.
Sodium Alginate – Soothing the Esophagus
Sodium alginate is an essential ingredient that helps prevent acid reflux by forming a protective layer.
How It Works:
- Reacts with stomach acid to form a viscous gel
- The gel floats on top of stomach contents, preventing acid from reaching the esophagus
- Provides additional protection against acid reflux and GERD
Sodium alginate-based formulations are especially useful for patients suffering from frequent nighttime acid reflux.
Other Common Ingredients in Antacid Suspensions
Calcium Carbonate & Magnesium Hydroxide
- Calcium Carbonate – A potent acid neutralizer that provides immediate relief from heartburn but may cause rebound acid secretion if overused.
- Magnesium Hydroxide – A gentle laxative effect helps prevent constipation, which is common with other aluminum-based antacids.
These ingredients are commonly found in the best antacids for heartburn, offering fast and long-lasting relief.
The Benefits of Antacid Suspensions Over Other Forms
Many patients choose antacid suspension syrup over chewable tablets or powders due to several advantages:
- Faster Absorption – Liquids work quickly compared to solid forms.
- Better Coating Effect – Suspensions form a protective layer over the stomach lining.
- Easier to Consume – Suitable for patients who struggle with swallowing pills.
- Balanced Composition – Ingredients like magaldrate minimize side effects.
For individuals suffering from chronic acid reflux, antacids for acid reflux in liquid form remain the most effective treatment.
Who Should Use Antacid Suspensions for Acid Reflux?
Antacid suspension is beneficial for:
- Individuals experiencing occasional heartburn
- Patients suffering from GERD (Gastroesophageal Reflux Disease)
- People who consume spicy or acidic foods frequently
- Pregnant women (after consulting a doctor)
- Individuals with difficulty swallowing pills
However, patients with kidney disease or low calcium levels should consult a doctor before using antacid suspension syrup.
Antacid Suspension vs. Other Acid Reflux Treatments
There are multiple treatments for acid reflux, and antacid oral suspension is one of the safest and most effective options.
Antacid Suspension vs. Proton Pump Inhibitors (PPIs)
- PPIs (like Omeprazole) work by blocking acid production, but they take time to show results.
- Antacid suspensions work instantly, making them preferable for immediate relief.
- Long-term PPI use can cause side effects such as bone loss, while antacid suspension is safer for regular use.
Antacid Suspension vs. H2 Blockers
- H2 Blockers (like Ranitidine, Famotidine) reduce acid production but do not act as quickly as antacids.
- Antacids for acid reflux provide instant relief, whereas H2 blockers take 30-45 minutes to work.
For quick, effective relief, antacid suspension syrup remains the best choice.
Choosing the Right Antacid Suspension Manufacturer
Selecting a trusted antacid suspension manufacturer is crucial for ensuring product quality and efficacy.
Key Factors to Consider:
- Manufacturing Standards – Ensure the manufacturer follows GMP and WHO quality guidelines.
- Formulation Expertise – Look for manufacturers experienced in magaldrate antacid benefits and advanced formulations.
- Third-Party Manufacturer for Antacids – Eskag Pharma offering third-party manufacturing services ensure customized formulations and private labeling.
- Pharma Contract Manufacturing for Antacid Suspension – Contract manufacturers specialize in large-scale antacid oral suspension production, ensuring cost-effectiveness.
For pharmaceutical companies looking to enter the antacid market, partnering with a reliable third-party manufacturer for antacids ensures high-quality products and compliance with regulatory standards.
Conclusion
Understanding antacid suspensions and their ingredients helps patients choose the right product for acid reflux relief. With magaldrate antacid benefits, sodium alginate protection, and other key ingredients, antacid suspension syrup offers fast and effective relief from heartburn.
When selecting an antacid suspension manufacturer, it is essential to partner with a trusted third-party manufacturer for antacids to ensure high-quality formulations and market success.
Would you like more insights into pharma contract manufacturing for antacid suspension? Contact a leading manufacturer today!
An antacid suspension is a liquid medication used to neutralize excess stomach acid and provide relief from acid reflux, heartburn, and indigestion. Unlike chewable or solid antacids, a suspension offers faster relief and better coating of the stomach lining, preventing irritation.
Antacid suspensions work by:
- Neutralizing excess stomach acid with ingredients like magaldrate, calcium carbonate, and magnesium hydroxide, reducing acidity.
- Forming a protective layer over the stomach lining and esophagus, preventing acid from causing irritation.
- Reducing gas and bloating with agents like simethicone, relieving digestive discomfort.
This triple-action formula makes antacid oral suspensions more effective than tablets in providing fast and long-lasting relief.
Yes! Antacid suspensions offer several advantages over tablets:
- Faster action – Works immediately as it doesn’t need to dissolve.
- Better coating effect – Protects the stomach and esophagus from acid.
- Comprehensive relief – Neutralizes acid, reduces gas, and soothes irritation.
- Easier to consume – Ideal for people who have difficulty swallowing pills.
For individuals suffering from frequent acid reflux, antacid suspension syrup is often considered the best antacid for heartburn.
Magaldrate is a key ingredient in many antacid suspensions because:
- It acts quickly to neutralize stomach acid.
- Provides long-lasting relief by releasing aluminum hydroxide and magnesium hydroxide gradually.
- Balances acid levels without causing rebound acid secretion (a common issue with calcium-based antacids).
- Has a low risk of constipation or diarrhea compared to other antacids.
Because of these properties, magaldrate antacid benefits make it a preferred choice for acid reflux relief.
The recommended dosage varies based on the formulation, but typically:
- For occasional heartburn – Take one dose after meals or when symptoms occur.
- For chronic acid reflux (GERD) – Follow a doctor’s prescription for long-term use.
Important: Avoid exceeding the recommended daily dose, as overuse may lead to electrolyte imbalances or nutrient absorption issues. Always consult a doctor before frequent use
Yes, many antacid suspensions are safe during pregnancy, but not all formulations. Pregnant women should:
- Choose calcium-based or magnesium-based antacids as they are safer.
- Avoid antacids containing sodium bicarbonate or aspirin, which may be harmful.
- Always consult a healthcare professional before using any antacid.
For pregnancy-related acid reflux, a mild antacid suspension syrup can provide quick relief without affecting the baby.
Antacid suspensions work within 5-10 minutes after consumption, providing quick relief from heartburn and acid reflux.
- Because it is a liquid, it doesn’t need time to dissolve like tablets.
- Coats the stomach lining immediately, offering soothing relief.
- Effects usually last for up to 2-3 hours.
For severe acid reflux, a doctor may recommend additional treatments, such as H2 blockers or PPIs.
While antacid suspensions are generally safe, excessive or prolonged use may cause:
Mild side effects:
- Nausea or bloating
- Temporary change in bowel habits (constipation/diarrhea)
Rare but serious side effects (due to overuse):
- Electrolyte imbalances (if taken excessively)
- Kidney issues (for patients with pre-existing kidney disease)
- Decreased absorption of certain medications (PPIs, antibiotics, iron supplements)
To avoid side effects, use antacid oral suspension as directed and consult a doctor for long-term use.
High-quality antacid suspension syrup is available at:
- Pharmacies & medical stores – Most over-the-counter (OTC) antacids are available without a prescription.
- Online marketplaces – Many e-commerce platforms sell antacid suspensions from reputable brands.
- Hospital & clinics – Some hospitals provide their own formulations of antacid suspension.
When buying, always check for:
- GMP & WHO certification
- Trusted manufacturers
- Proper expiry date & ingredient list
If you need bulk orders or private labeling, consider working with a third-party manufacturer for antacids.
If you’re looking for a trusted third-party manufacturer for antacids, consider the following:
- GMP & WHO certification – Ensures high-quality production standards.
- Experience in pharma contract manufacturing for antacid suspension – Proven expertise in liquid formulations.
- Custom formulation options – Ability to develop unique antacid oral suspension with market differentiation.
- Regulatory compliance – Meeting FDA, CDSCO, and other pharma guidelines.
If you are a pharma company looking for contract manufacturing services, partnering with a reliable antacid suspension manufacturer can help expand your product portfolio and market reach.